Indications and therapeutic-medical experiences made with ­Mutaflor and Overview of the pertinent studies

The current marketing authorizations as well as the clinical studies and casuistics all reveal the broad application spectrum of ­Mutaflor. For you, we have compiled the most important fields of application and study results. Please refer the navigation at the left side.

Clinical studies, experiential reports and casuistics

According to current marketing authorizations (­Mutaflor, ­Mutaflor Suspension)
  •  Ulcerative colitis in the phase of remission
  •  Chronic constipation
  •  Colonization prophylaxis in premature and full-term infants
  •  Enhancement of postnatal immune competence in premature and full-term infants
  •  Diarrhea in infants, toddlers and children
  •  Diarrhea in infants, toddlers and children under gastric tube feeding
According to clinical studies
  • Crohn's disease
  • Pouchitis
  • Collagenous colitis
  • Antibiotic-associated colitis/pseudo-membranous colitis
  • Irritable bowel syndrome
  • Diverticulosis
  • Polymorphous photodermatosis
According to experiential reports/casuistics
  • Non-ulcer dyspepsia
  • Dietary intolerance/malabsorption
  • Halitosis
  • Susceptibility to infection
  • Mycoses of the gastrointestinal tract
  • Other, e. g. neurodermitis, reactive arthritis, radiation enteritis/radiation colitis, recurrent urinary tract infections

Overview of the pertinent studies

Diarrhea: Henker et al. 2007, 2008 39; 40
Irritable bowel syndrome: Krammer et al. 2006 52, Plassmann 2007 53, Keller et al. 2010 50, Kruis et al. 2012 29
Antibiotic-associated colitis/pseudomembranous colitis: Goerg u. Schlörer 1998 54, Goerg et al. 2008 55
Ulcerative colitis: Kruis et al. 1997 43, Rembacken et al. 1999 44, Kruis et al. 2004 45, Henker et al. 2008 46, Matthes et al. 2010 47
Crohn's disease: Malchow 1997 49
Pouchitis: Kuzela et al. 2001 56
Collagenous colitis: Tromm et al. 2004 57
Chronic constipation: Bruckschen et al. 1994 42, Möllenbrink et al. 1994 41
Diverticulosis of the colon: Fricˇ et al. 2003 58
Colonization prophylaxis and enhancement of immune competence in full-term and premature neonates: Lodinová-Žádníková et al. 1992 35, Lodinová-Žádníková und Sonnenborn 1997 36, Schröder 1992 3, Cukrowska et al. 2002 37
Intestinal-dependent halitosis: Henker et al. 2001 59
Polymorphous photodermatosis: Wurzel 1999 60

Mutaflor international package insert to download
Mutaflor Suspension international package insert to download