Clinical effects of E. coli strain Nissle 1917 in case Crohn's disease
Malchow treated 28 patients with active Crohn's disease of the colon over one year with prednisolone and with an adjuvant therapy of Mutaflor versus placebo. 49 After remission had been reached, less relapses occurred in the patient group treated with Mutaflor than in the control group (33.3 % versus 63.6 %).
In addition, the adjuvant administration of Mutaflor elicited a steroid sparing effect.
Mutaflor versus Placebo in cases of Crohn’s disease 49
Stratum I = colon disease
49) Malchow HA. Crohn‘s Disease and E. coli. J Clin Gastroenterol 1997; 25: 653–658