Mutaflor – the natural treatment of chronic constipation
Two controlled clinical Mutaflor studies are available for the indication of chronic constipation.
Mutaflor versus Placebo
- 8-week study
- 70 patients
- patients having received Mutaflor had a significantly higher weekly stool frequency than the 35 patients who had received the placebo.41
stool frequency per week

Mutaflor versus Lactulose
- 12 weeks study
- 108 Patients
- the efficacy of Mutaflor and lactulose was comparable after the treatment 42
Mutaflor versus Lactulose – regular consistency, ease of defecation, side effects and stool frequency

41) Möllenbrink M, Bruckschen E. Behandlung der chronischen Obstipation mit physiologischen Escherichia-coli-Bakterien. Med Klin 1994; 89:587–593.
42) Bruckschen E, Horosiewicz H. Chronische Obstipation, Vergleich von mikrobiologischer Therapie und Lactulose. Münch Med Wochenschr 1994;16:241–245.